Ursula Seidler Selected Research

Sodium-Hydrogen Exchanger 3

1/2022	Sodium/hydrogen-exchanger-2 modulates colonocyte lineage differentiation.
1/2012	Loss of downregulated in adenoma (DRA) impairs mucosal HCO3(-) secretion in murine ileocolonic inflammation.
10/2002	The down regulated in adenoma (dra) gene product binds to the second PDZ domain of the NHE3 kinase A regulatory protein (E3KARP), potentially linking intestinal Cl-/HCO3- exchange to Na+/H+ exchange.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Ursula Seidler Research Topics

Disease

15	Inflammation (Inflammations) 06/2022 - 08/2006
11	Diarrhea 01/2022 - 08/2006
8	Colitis 01/2020 - 12/2007
6	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2022 - 11/2005
6	Ulcerative Colitis 01/2021 - 07/2010
6	Cystic Fibrosis (Mucoviscidosis) 01/2019 - 02/2009
5	Crohn Disease (Crohn's Disease) 10/2018 - 06/2010
5	Adenoma (Adenomas) 01/2012 - 03/2002
4	Body Weight (Weight, Body) 01/2019 - 11/2005
3	Acidosis 01/2021 - 10/2009
3	Hypertension (High Blood Pressure) 02/2009 - 08/2008
2	Neoplasms (Cancer) 06/2022 - 03/2011
2	Necrosis 01/2021 - 01/2017
1	Metaplasia 06/2022
1	Congenital chloride diarrhea 01/2022
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2022
1	Dysbiosis 01/2022
1	Fibrosis (Cirrhosis) 01/2022
1	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2020
1	Behcet Syndrome (Behcet's Syndrome) 01/2020
1	Fever (Fevers) 01/2020
1	Ulcer 01/2020
1	Oral Ulcer (Mouth Ulcer) 01/2020
1	Nutrition Disorders (Nutritional Disorders) 01/2020
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2019
1	Hyperaldosteronism (Conn Syndrome) 01/2019
1	Short Bowel Syndrome 01/2019
1	Ileitis 10/2018
1	Wounds and Injuries (Trauma) 07/2017
1	Intestinal Failure 01/2016
1	Infections 12/2014
1	Pancreatitis 03/2014

Drug/Important Bio-Agent (IBA)

8	CytokinesIBA 01/2022 - 09/2008
8	Proteins (Proteins, Gene)FDA Link 01/2022 - 10/2002
6	SaltsIBA 01/2018 - 08/2008
6	AnionsIBA 01/2016 - 03/2005
5	Phenobarbital (Luminal)FDA Link 01/2022 - 12/2007
5	ChloridesIBA 10/2020 - 08/2008
5	Sodium-Hydrogen ExchangersIBA 10/2019 - 05/2009
4	ElectrolytesIBA 10/2020 - 08/2006
4	Dextrans (Dextran)FDA Link 01/2020 - 12/2007
4	Dextran SulfateIBA 01/2020 - 09/2008
4	SodiumIBA 01/2019 - 12/2007
3	Sodium-Hydrogen Exchanger 3IBA 01/2022 - 10/2002
3	Messenger RNA (mRNA)IBA 01/2021 - 01/2012
3	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2020 - 12/2007
3	Protein Isoforms (Isoforms)IBA 01/2019 - 05/2009
3	Interleukin-23 (Interleukin 23)IBA 10/2018 - 11/2016
3	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 01/2012 - 01/2009
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2012 - 07/2010
3	FructoseIBA 02/2009 - 08/2008
2	Bicarbonates (Hydrogen Carbonate)IBA 01/2022 - 04/2013
2	Tumor Necrosis Factor InhibitorsIBA 01/2021 - 01/2017
2	Pharmaceutical PreparationsIBA 01/2020 - 03/2011
2	DipeptidesIBA 01/2020 - 01/2016
2	risankizumabIBA 10/2018 - 01/2017
2	Monoclonal AntibodiesIBA 01/2017 - 11/2016
2	AcidsIBA 12/2012 - 10/2009
2	ColforsinIBA 12/2012 - 01/2009
2	Epithelial Sodium ChannelsIBA 01/2012 - 04/2011
2	Phosphotransferases (Kinase)IBA 11/2010 - 10/2002
1	RNA (Ribonucleic Acid)IBA 06/2022
1	Chloride-Bicarbonate AntiportersIBA 01/2022
1	Antimicrobial PeptidesIBA 01/2022
1	carbonic anhydrase XIVIBA 01/2022
1	Biological ProductsIBA 01/2021
1	vedolizumabIBA 01/2021
1	GLPG0634IBA 01/2021
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2021
1	Immunosuppressive Agents (Immunosuppressants)IBA 01/2021
1	Protons (Proton)IBA 01/2021
1	Janus Kinase 1IBA 01/2021
1	HMGB1 Protein (HMG1)IBA 01/2020
1	Interleukin-17 (Interleukin 17)IBA 01/2020
1	Toll-Like Receptor 4IBA 01/2020
1	linaclotideIBA 01/2020
1	veltuzumabIBA 01/2020
1	Neutralizing AntibodiesIBA 01/2020
1	Virulence Factors (Pathogenicity Factors)IBA 10/2019
1	heat stable toxin (E coli)IBA 10/2019
1	AldosteroneIBA 01/2019
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 08/2018
1	Biomarkers (Surrogate Marker)IBA 08/2018
1	andecaliximabIBA 08/2018
1	Therapeutic UsesIBA 01/2018
1	Fluorescent Dyes (Fluorescent Probes)IBA 07/2017
1	Ustekinumab (CNTO 1275)FDA Link 11/2016
1	Interleukin-12 (IL 12)IBA 11/2016
1	Toll-Like Receptor 9IBA 11/2016
1	DNA (Deoxyribonucleic Acid)IBA 11/2016
1	DIMS0150IBA 11/2016
1	sodium-hydrogen exchanger regulatory factorIBA 08/2015
1	Small Interfering RNA (siRNA)IBA 08/2015
1	FlagellinIBA 12/2014
1	Fimbriae Proteins (Pilin)IBA 12/2014
1	Drinking WaterIBA 01/2014

Therapy/Procedure

5	Therapeutics 01/2021 - 11/2016
1	Intraperitoneal Injections 01/2020
1	Bariatric Surgery 01/2019
1	Enema (Enemas) 01/2014